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16.3 芳环的烷基化与酰基化:傅-克反应

实验室中最有用的亲电芳香取代反应之一是烷基化——即将烷基引入苯环。该反应以发现者命名,称为傅-克反应(Friedel–Crafts反应),由

1. Among the most useful electrophilic aromatic substitution re

Among the most useful electrophilic aromatic substitution re

2. Another limitation is that Friedel–Crafts reactions don’t su

Another limitation is that Friedel–Crafts reactions don’t su

3. A final limitation to the Friedel–Crafts reaction is that a

A final limitation to the Friedel–Crafts reaction is that a

4. The mechanism of Friedel–Crafts acylation is similar to that

The mechanism of Friedel–Crafts acylation is similar to that

5. An example of a biological Friedel–Crafts reaction occurs du

An example of a biological Friedel–Crafts reaction occurs du

6. Part 6

Part 6

7. Worked Example 16.1: Predicting the Product of a Carbocation Rearrangement

Worked Example 16.1: Predicting the Product of a Carbocation Rearrangement

8. Part 8

Part 8

9. Part 9

Part 9

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