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21.2 亲核酰基取代反应

亲核试剂加成到极性 C═O 键上是羰基四大反应中三个反应的关键步骤。我们在《醛和酮：亲核加成反应》一章中已经看到

1. The addition of a nucleophile to a polar C═O bond is the key

The addition of a nucleophile to a polar C═O bond is the key

2. The net effect of the addition/elimination sequence is a sub

The net effect of the addition/elimination sequence is a sub

3. Relative Reactivity of Carboxylic Acid Derivatives

Relative Reactivity of Carboxylic Acid Derivatives

4. The way in which various substituents affect the polarizatio

The way in which various substituents affect the polarizatio

5. Reaction | Yield - • Hydrolysis | Reaction with water to yie

Reaction | Yield - • Hydrolysis | Reaction with water to yie

6. Part 6

Part 6

7. Worked Example 21.1: Predicting the Product of a Nucleophilic Acyl Substitution

Worked Example 21.1: Predicting the Product of a Nucleophilic Acyl Substitution

8. Part 8

Part 8

9. Part 9

Part 9

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