Organic Chemistry · 免费预览
21.7 酰胺的化学
酰胺与酯一样，在所有生物体中大量存在。蛋白质、核酸以及许多药物制剂都含有酰胺官能团。酰胺之所以如此丰富，是因为它们在生物体所处的水性条件下是稳定的。酰胺是常见酸衍生物中反应性最低的，发生的亲核酰基取代反应相对较少。
1. Amides, like esters, are abundant in all living organisms. P
Amides, like esters, are abundant in all living organisms. P
2. Preparation of Amides
Preparation of Amides
3. Reactions of Amides
Reactions of Amides
4. Conversion of Amides into Carboxylic Acids: Hydrolysis
Conversion of Amides into Carboxylic Acids: Hydrolysis
5. Amide hydrolysis is common in biological chemistry. Just as
Amide hydrolysis is common in biological chemistry. Just as
6. Conversion of Amides into Amines: Reduction
Conversion of Amides into Amines: Reduction
7. The reaction is effective with both acyclic and cyclic amide
The reaction is effective with both acyclic and cyclic amide
8. Part 8
Part 8
9. Worked Example 21.4: Synthesizing an Amine from an Amide
Worked Example 21.4: Synthesizing an Amine from an Amide
10. Part 10
Part 10